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Peganum Harmala (Syrian Rue)

Peganum Harmala (Syrian Rue)

About Peganum Harmala (Syrian Rue)

Peganum Harmala is also known as Syrian Rue. This plant belongs to the Nitrariaceae family (botanical name) and originates in warm and dry areas. This plant is used for many purposes in different cultures. For example, it is used in Turkey against the "evil eye" and in India and Pakistan for gynaecological purposes. But Syrian Rue is also known for its ability to reinforce the effect of psychedelics. An average dose of Perganum Harmala has an enhancing effect on Magic Truffles. Attention! We recommend that you try this only when you are an experienced user of Magic Truffles or Magic Mushrooms.

In the West it is mainly used for its strong monoamino oxidase inhibition.

Effects of Peganum Harmala (Syrian Rue)

Peganum Harmala has a strong MAO inhibitory effect but gives a different effect to the Ayahuasca than Banisteriopsis Caapi. That's why the name of Anahuasca is also given to the brew made with Syrian Rue, it is a surrogate of the Ayahuasca. Many people prefer this variant because the physical effects are less vigorous and the seeds are also easier to process. Due to its MAO inhibitory effect, Peganum Harmala is mainly used in combination with other DMT-based plants.


If you want to use Peganum Harmala as an MAO inhibitor, you should use 3 grams. Take the seeds about 15-60 minutes before taking the psychoactive substance you wish to use. The effects of the Syrian Rue will last about 3 to 4 hours. You can take Syrian Rue in different ways. If you choose the seeds, you can simply eat them by chewing them. If you prefer gel capsules, you can first grind the seeds and make capsules. Finally, you can also make tea, which is also softer for your stomach. For this take 200 ml of water and 50 ml lemon juice, 3-4 grams of seeds and let it boil for about half an hour in the water with lemon on a low fire. Pour the tea through the sieve and it is ready to drink.


  • Seeds: 20 grams
  • 10x extract: 1 gram 10x concentrated extract of Peganum Harmala (1 gram of extract equals about 10 grams of seeds)

Peganum Harmala is also available in 2 complete Ayahuasca Mixes:

Average dose for 1 trip

Seeds: about 3 to 4 grams.


Peganum Harmala is a natural product. The strength can vary per gram. Brewing Ayahuasca is a matter of trying out which dose and what way works best for you. There are many different recipes available on the internet and in shaman books.


Peganum Harmala contains MAO inhibitors and can be very dangerous in combination with certain psychoactive substances and food, which are usually not harmful when taken by their own. Therefore make sure not to take any of these substances or food less than 12 hours before ingestion of Ayahuasca. Ayahuasca is not a party drug. Use it in a quiet, familiar environment, preferably with an experienced sitter, a sober person who can take care of you. Do not use when pregnant, breastfeeding, depressed, psychotic, operating motorized vehicles or heavy machinery, or in combination with alcohol or medicines. Not to be used by minors.

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